Thursday, December 23, 2004

Nanotechnology comes to golf balls

Sometime in 2005, start-up company NanoDynamics plans to sell a nanotech golf ball that promises to dramatically reduce hooks and slices for even the most frustrated of weekend golfers.....

That will be a hint of the future of sports.

NanoDynamics says it's figured out how to alter the materials in a golf ball at the molecular level so the weight inside shifts less as the ball spins. The less it shifts, the straighter even a badly hit ball will go.

"It's all about controlling the physics of how the ball spins," says CEO Keith Blakely.

Nanotechnology — engineering on a scale of individual atoms — is a way to make new materials, or to improve properties of existing materials. Its uses range from medical devices to car paint. And in the past, any shift in materials science has eventually altered sports.

Think of tennis rackets. Until a few decades ago, they were made of wood. Wilson figured out how to make a metal racket and in 1967 introduced the breakthrough T2000. By 1980, high-end rackets were made of graphite. As the materials got stiffer and lighter, the game began to favor speed and power serves.

Think, too, of aluminum baseball bats, composite skis, plastic (instead of leather) football helmets and Astroturf. All emerged from new materials and changed their games.

Now it's nanotech's turn. The science is still young, and so far only a few nanotech-based sports products have hit the market. A Japanese company makes a bowling ball that supposedly won't get surface nicks yet sticks to the center of the lane the same as traditional balls. Wilson uses nanotech to make tennis balls that deflate less quickly, and several companies are working on nanotech golf clubs. A French company makes a nano-engineered tennis racket.

Much more will come.

Nanotechnology can make material stronger and lighter than ever — "and sporting goods is all about 'stronger and lighter,' " says Bob Thurman, director of research for Wilson Global Golf. Nanotech will eventually make better-performing yacht racing masts, hockey sticks, vaulting poles, softball bats, golf clubs and tennis rackets. The technology will help make lighter racing bikes and Indy cars.

Eventually, nanotech could produce some truly exotic sports products. Nanosys, one of the most successful nanotech companies, has come up with a nano-engineered coating far slicker than Teflon. Water literally bounces off it. Today, Nanosys is working only on industrial uses for the coating. But if the coating could be made to cover one of those all-body swimsuits, a swimmer might practically skim across the pool.

Nanotechnology comes of age
Nanotechnology has been an area of serious research in university and industrial labs for more than a decade. Over the past few years, nanotech start-ups have begun to dot the business landscape. Some of the first products have reached the market — mostly industrial uses, such as car paint that adheres better.

Like "atomic" in the 1950s, "micro" in the 1980s and the ".com" suffix in the 1990s, "nano" is becoming a hot new label. Companies use it in their names — Nanosys, NanoDynamics. Marketers are starting to throw it on products.

It's a broad term. Nanotech can refer to anything engineered down to the nanometer. A nanometer is one-billionth of a meter, which is only three to five atoms across.

Nanotech is being used to make tiny lenses in optical switches to redirect light from one fiber-optic cable into another. It's emerging as a way to make solar panels that are far more efficient than any current technology. One company, Nano-Tex, has engineered cotton fibers so they resist water yet still feel like cotton. Eddie Bauer now sells the company's Nano-Care khakis.

Sports Gear Could Be Four Times Better
Sports seems to be nanotech's next frontier. One hot area of interest is in carbon nanotubes — an engineered matrix of carbon molecules that creates a substance up to 100 times stronger than steel, at one-sixth the weight. Nanotubes are the next leap up the trajectory that went from wood to metal or fiberglass and then to graphite — every step getting lighter, stronger and less likely to break.

"It's amazing in sports how much just incremental increases in performance can mean," says Jim Von Ehr, CEO of nanotech company Zyvex. Sports equipment makers are happy when a product is 10% to 20% better; nano-materials can make some items perhaps four times better, he says.

That might not sit well with sports governing bodies, which in the past have restricted some new technologies because of concerns about how the sport and its records might be altered. For instance, Major League Baseball doesn't allow aluminum bats.

Some tennis experts, such as former star John McEnroe, argue that modern rackets have ruined the game by making men's serves almost impossible to return.

Sporting goods experts say a carbon nanotube racket could boost serve speeds significantly higher yet.

Big Impact In Sports Still A Ways Off
There hasn't yet been a flood of nanotech sports products because the technology is still expensive and difficult. Plus, sports marketers are still trying to figure out how to pitch nanotech products and how much demand there will be from sports enthusiasts.

"Nanotech's now just not sexy enough," says Wilson's Thurman. A nanotech club or racket probably wouldn't look much different from ones made of graphite. "Going from a wood racket to metal — that's sexy," Thurman adds. "Visible technology is key in sporting goods."

The size of the nanotech sports product market so far is negligible — so small that none of the better-known nanotech watchers have bothered to measure it. Nanotech in general is just emerging as an industrial force. In 2004, $13 billion worth of products will incorporate nanotechnology, less than 0.1% of global output, according to the NanoBusiness Alliance trade group. But by 2014, that figure is expected to rise to $2.6 trillion, or 15% of that year's manufacturing output.

Yet at this early stage, a number of nanotech sports products are poking into the market.

Golf
Wilson is using a nano-composite material to replace the titanium crown on the Wilson Staff Driver. That makes the top part of the driver lighter, lowering the center of gravity — which helps the golfer achieve more power and accuracy, Wilson says. The company is also using nanotech to strengthen golf shafts, but, "The problem is, it's extremely expensive to manufacture nanotech shafts," Thurman says.

AccuFlex, which makes only shafts, in August introduced its Evolution nanotech golf club shaft.

Next could come nano golf balls. NanoDynamics, based in Buffalo, won't divulge many details about its upcoming ball. Until now, it hasn't publicly revealed anything about the ball, which the company plans to make and sell for $7 to $8 apiece. The most expensive ball on the market today is about $5. Most golfers pay $1 to $2 a ball.

But the company says the balls could make such a difference — and, for instance, result in fewer lost balls — that golfers would pay the steep price. NanoDynamics says it's working with the U.S. Golf Association to make sure the balls are legal.

Wilson and other companies are also adding nanotech substances to golf ball cores, though they don't claim the makeover promised by NanoDynamics.

Tennis
Wilson earlier this month introduced its nCode racket, which uses nanotubes. French company Babolat is selling a $180 nano-racket that it claims is five times stiffer than carbon rackets.

Wilson and New Jersey-based InMat say they've used nanotech to improve the tennis ball. Based on research at Cornell University, InMat's technology forces 1-micron balls of butyl rubber to mix and bond with clay particles. It creates a coating that's flexible but nearly airtight. That means tennis balls can keep their bounce longer once the can is opened.

Biking
Easton Sports and Zyvex are working together to put carbon nanotubes into bicycle parts. So far, they have used them only in handlebars, making them stronger and lighter. The material, says Zyvex CEO Von Ehr, "is very difficult to process." But it can shave 15% to 20% off the weight — a big deal to a pro bike racer.

Bowling
Japanese company Nanodesu (which, translated, means "It's nano!") is using a nanotech material called fullerenes as a super-hard coating on bowling balls. The company says it prevents chipping and cracking but performs like a typical polyurethane ball.

Say goodbye to smelly gym clothes?

Few other nanotech sports products have yet come to market — other than peripheral products, such as nanotech-enhanced ski wax, sunglasses and sun block.

People in the sporting goods and nanotech industries, though, are constantly knocking around ideas for using nanotech in sports. Zyvex says it's talking "to every conceivable sporting goods company" about products such as hockey sticks, helmets and racing yacht masts.

Wilson only recently started selling all-graphite softball bats for $200 to $300. It's interested in using nanotech to make those bats lighter and stronger — and perhaps pricier.

Just about anything is possible. In fact, nanotech will probably be used to solve one of the oldest problems in sports: smelly equipment and clothing.

NanoHorizons of State College, Pa., this fall said it developed silver nano-particles that can mesh with the cotton, plastic or nylon material in shoes, pads, jerseys, helmets, socks or other pieces of sports equipment. The metals kill the bacteria and microbes that cause odors.

"I know a whole lot of moms who would love to see this incorporated into hockey gear, which gets pretty ripe," says Blakely, a hockey dad as well as a nanotech CEO.

Source - NanoDynamics


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Scientists disclose Santa's work secrets

By Seth Borenstein Washington Bureau

Employing Albert Einstein's theory of relativity, Santa can zip around the world warping
time and space and turning Rudolph's nose a blurry blue.
Scientists calculate the jolly old elf may be aided by computer-generated trip-planners,
antennas to read children's brain waves and nanotechnology that can make toys from cookies
or dirt......
For the past several years, a handful of holiday-hearted physicists, engineers and
biologists have theorized as to just how Kris Kringle performs his yearly Christmas miracle
while obeying the laws of physics.
Larry Silverberg, a professor of mechanical and aerospace engineering at N.C. State
University, came up with the most detailed answer to an engineering challenge "that seems
almost impossible."
The key to Santa's travel is what Silverberg calls "a relativity cloud," in which Santa
learned how to bend time, space and light - essentially making clocks run more slowly for
him than for the rest of us.
Walking through a child's house may take Santa several minutes, "but to us it would seem
like a wink of the eye," Silverberg said.
Arnold Pompos, a physics researcher at the Fermi National Accelerator Laboratory, six years
ago came up with a slightly different version. He has Santa traveling at 99.9999999 percent
of the speed of light, delivering all his presents in about 500 seconds. The rest of the
night he can feast on cookies and milk.
At that speed, Santa would leave a trail of light across the dark sky, and Rudolph's nose
would change from red to blue in a phenomenon called the Doppler shift.
To help Santa get to places more efficiently, mathematicians have come up with possible
routings to tens of thousands of cities. In September, Danish computer scientist Keld
Helsgaun came up with one that's considered the most efficient to date, allowing Santa to
visit more than 1.9 million locations worldwide while traveling just slightly more than 4.67
million miles.
Silverberg said Santa may be able to figure out what toys children want by using underground
antennas that read children's brain waves, like superevolved EKGs.
And instead of carrying bags loaded with presents, Santa could use nanotechnology, a field
of molecule-sized engineering, to turn dirt and debris into toys, Silverberg said.
It all may sound fantastic, Silverberg said, but "we know this kind of stuff is possible."

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A little individual indulgence about Scotland. Thanx Volker for finding this.

vowe dot net: "Skye Bridge tolls are abolished
by Volker Weber
When we visited Skye this summer, I was really surprised by the amount of money you had to spend for crossing the bridge between the Scottish mainland and the isle of Skye. Now the toll has been abolished:
The Scottish Executive has abolished the controversial Skye Bridge tolls. The government announced an end to the charges on Tuesday morning after it bought back the bridge from its private owners for �27m.
More >
2004-12-21 :: "

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bookofjoe: P2P's successor - C2C?

bookofjoe: P2P's successor - C2C?: "Car-2-Car Communications Consortium, currently developing the new new thing in car technology." BMW, Fiat, Audi, Daimler-Chrysler, Volkswagen, and Renault have banded together to explore ways for cars of the future to warn each other of accidents and danger spots and automatically find new routes to avoid congestion.

They hope to create vehicles that can communicate via WiFi.

They hope to move from passive to active, in terms of avoidance and safety.
In the future, the system could automatically pre-tense the brakes in nearby cars, speeding the driver's reaction time, or instruct navigation computers in more distant vehicles to find alternative routes.

The WiFi technology would bounce information from car to car, using relatively short-range technology to create a large network of vehicles.
Full article

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Wednesday, December 22, 2004

HIPPA is at fault for daughters death.

Medpundit: "Near the end of her short life, Shayla Stewart, a diagnosed manic-depressive and schizophrenic, assaulted police officers and was arrested for attacking a fellow customer at a Denton Wal-Mart where she had a prescription for anti-psychotic medication.

Given all those signs, her parents say, another Wal-Mart just seven miles away should have never sold her the shotgun she used to kill herself at age 24 in 2003.

Her mother, Lavern Bracy, is suing the world's biggest store chain for $25 million, saying clerks should have known about her daughter's illness or done more to find out.

Pharmacy prescription records are subject to federal privacy rules. No one can gain access to those without written permission from the patient. (With some exceptions, such as law enforcement agents investigating a crime.) Buying a gun isn't a crime,though. And the Wal-Mart did ask her about mental illness, but she lied. What's more, although federal law prohibits selling guns to mentally ill people, according to the story, 38 states prohibit release of information about mental illness. It's hard to see how it's Wal-Mart's fault that she killed herself. Without a gun, she surely would have found another method.

posted by sydney smith on 12/22/2004 12:52:01 PM link "

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The newest medical tool: an iPod

SoloDoc: "How's this for convergence? Radiologists at UCLA (Go Bruins!) have figured out an excuse a way to use iPods in their medical practice. Their (free!) product is called OsiriX and helps to manage medical images on the iPods hard drive."

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IE Crashes, is it attributed to Google

Faughnan's Notes: "IE crashing -- is it the google toolbar? My, how strange would that be ...
Google Toolbar

IE has started crashing on me. It's never done that before. Maybe IE feels bad that I've left it for Firefox?

Or is it the Google toolbar? Last time IE crashed, it kindly told me, as a part of the post-crash report, that I had the Google Toolbar installed. It didn't say I should remove it. Of course IE has never before had a problem with the Google Toolbar. The only way that COULD happen would be if one of those endless IE patches had, as a most unfortunate side-effect, an incompatibility with the Google Toolbar.

Nahhh. Microsoft has never done anything like that before. Have they?

[cue: evil, diabolical, echoing, laughter]

// posted by John on 12/22/2004 Persistent Link"

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InsideGoogle

InsideGoogle: "Celebrex Soars, At Least In Ad Dollars
Celebrex, the keyword, has soared, as personal injury attorneys scramble to buy the keyword for big bucks at Overture and AdWords, MarketWatch is reporting. The Overture cost of Celebrex soared from 95 cents on Friday to $4.02 today, following news that the FDA was considering regulatory measures for the best-selling arthritis drug. Celebrex is expected to top ten dollars, but not reach the heights of Vioxx, which reched $40 per click within two weeks of its withdrawl from the market. Vioxx still sells at about $9.
(via Search Engine Watch)
- posted by Nathan Weinberg @ 12/20/2004 05:12:49 PM 0 comments
"

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Microsoft

Remedies may not help Microsoft's competitors - Computerworld: "On March 24, the commission gave Microsoft 90 days to unbundle its media player software from its operating system and sell a version of Windows without Windows Media Player, and 120 days to give its competitors access on reasonable and nondiscriminatory terms to the technical interface information needed to make non-Microsoft workgroup servers interoperable with Windows PCs. "

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PCWorld.com - Google Smacks Down Santy Worm

PCWorld.com - Google Smacks Down Santy Worm: "Google Smacks Down Santy Worm

Search engine's actions should halt the worm's spread, antivirus vendors say.
Paul Roberts, IDG News Service
Wednesday, December 22, 2004
Web search engine company Google is blocking efforts by a new Internet worm to use its search engine to find vulnerable computers on the Internet, the company announced this week."

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Technology News: Health : Terminal Patients Don't Hang on Until After Holidays

Technology News: Health : Terminal Patients Don't Hang on Until After Holidays: "Terminal Patients Don't Hang on Until After Holidays

By Liz Szabo
USA Today
12/22/04 10:10 AM PT
Researchers singled out the deaths of more than 300,000 cancer patients, because deaths from cancer are usually more predictable and less sudden than those from heart attacks, strokes or other ailments. There was no increase in overall mortality after Christmas."

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My brothers joke.

Q Whats the hardest part about eating a vegetable? A The wheelchair!

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Techdirt:When Coffee Goes High Tech

Techdirt:When Coffee Goes High Tech: "Hot Ice
by dorpus on Monday, December 20th, 2004 @ 02:48AM

In an opposite (?) development, a Japanese team discovered that water forms ice crystals inside of carbon nanotubes, even above room temperature (27 C). It's the first time that ice has been observed at this temperature, without extreme pressure. When the nanotubes were heated to 45C, the ice rapidly evaporated. It may have uses in inkjet printers.

http://flash24.kyodo.co.jp/?MID=RANDOM&PG=STORY&NGID=soci&NWID=2004122001002426"

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When Coffee Goes High Tech

Techdirt:When Coffee Goes High Tech: "Contributed by Mike on Monday, December 20th, 2004 @ 02:00AM
from the head-for-the-hills dept.
Apparently coffee was in need of a jolt of high tech inspiration. Starting in just a few weeks you'll be able to buy a product that most of you probably never thought was necessary at all: a single serving can of coffee that heats itself. The idea is that you buy the can, and when you're ready to drink it, you push a button, and it heats itself up. No batteries or electricity needed. Just push the button, let the calcium oxide (yum!) mix with water, and voila, you have a steaming hot cup of joe. Who knew that heating up water was too difficult? "

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Tuesday, December 21, 2004

World's tiniest baby doing well in Chicago


Neonatalogist Dr. Jonathan Muraskas places his hand next to Rumaisa Rahman, known to be the smallest baby in the world to survive birth, in this file photo taken three weeks after birth, at Loyola Medical Center in Maywood, Illinois. Rahman weighed 8.6 ounces at birth, about the size of a cellular phone. [Reuters]
A premature infant believed to be the smallest baby ever to survive was called "a great blessing" Tuesday by her mother, who is preparing to take the little girl and her twin sister home from the hospital....
The baby, named Rumaisa, weighed 8.6 ounces ¡ª less than a can of soda ¡ª when she was delivered by Caesarean section Sept. 19 at Loyola University Medical Center. That is 1.3 ounces smaller than the previous record holder, who was born at the same the hospital in 1989, according to hospital spokeswoman Sandra Martinez.

Rumaisa, her twin, Hiba, and their parents were introduced Tuesday at a news conference at the hospital in suburban Maywood. The girls were bundled in identical striped blankets.

Their mother, Mahajabeen Shaik, said she didn't "have the words to say how thankful I was" when she first got to hold her children in their second month.

"It's a blessing, it's a great blessing," she said.

Hospital officials said they are doing so well that Hiba, who weighed 1 pound and 4 ounces at birth, could be released from the hospital by the end of this month, with Rumaisa following as early as the first week of January.

Rumaisa now weighs 2 pounds, 10 ounces. Her twin weighs 5 pounds.

"They're maintaining their temperature; they don't need an incubator. They're taking their bottles," said Dr. William MacMillan. "They're normal babies."

Shaik, 23, developed pre-eclampsia, a disorder characterized by high blood pressure and other problems, during pregnancy. The condition endangered Rumaisa and her mother, prompting a C-section at 26 weeks. Normal gestation is 40 weeks.

Dr. Jonathan Muraskas, a professor of neonatal-perinatal medicine, said several factors may have improved the babies' chances of survival. Babies born before 23 weeks do not have fully developed lungs and are usually not viable, but those born afterward can survive.

Muraskas said girls are also more likely to survive than boys when born at less than 13 ounces, and the twins could have been helped by their mother's health problems. "Sometimes, when babies are stressed in utero, that can accelerate maturity," he said.

Muraskas said the twins were placed on ventilators for a few weeks and fed intravenously for a week or two until nurses could give them breast milk through feeding tubes. They were able to start drinking from bottles after about 10 weeks.

Ultrasound tests have shown no bleeding in Rumaisa's brain, a common complication in premature babies that can raise the risk of cerebral palsy. Both girls also underwent laser surgery to correct vision problems common in preemies.

Shaik and her husband, Mohammed Abdul Rahman, 32, said they are looking forward to bringing their children home. The couple, originally from Hyderabad, India, live in the suburb of Hanover Park.
"We want them to be good human beings, good citizens, and she wants them to be doctors," said Rahman, looking at his wife.

"Doctors. Yes, of course, of course," she said, laughing.

Madeline Mann, the previous record holder as smallest known surviving preemie, returned to Loyola Hospital earlier this year for a celebration. Now 15, she was described as a lively honor student, though small for her age, at 4-feet-7.

According to the hospital, more than 1,700 newborns weighing less than 2 pounds have been cared for there in the past 20 years.

Stephen Davidow, a hospital spokesman, said a routine delivery costs about $6,000, while caring for a premature baby costs about $5,000 a day. Rumaisa, who has been in the hospital 90 days, is covered by Medicaid, hospital officials said.




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A Closer Look at Aleve

A new study, designed to test whether Aleve reduces the risk of Alzheimer's, found that the medicine could increase other risks. Those taking Aleve had a fifty percent greater incidence of heart attack or stroke than those taking a placebo.
The FDA is urging consumers to follow label guidelines. Don't use Aleve for more than ten days in a row, and don't take more than three pills in any given 24-hour period.

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Mobile Viruses Emerge

Symantec continues to monitor the development of malicious code on portable devices. (Think: Cabir-the first worm to infect Sybion OS smart phones using bluetooth to replicate, and Duts.A-the first parasitic infector of portable executable files on Windows CE, and Brandor.A-the forst backdoor trojan to target windows mobile OS (discovered August 5th 2004.) Duts.A demonstrates that virus techniques that appeared in PC viruses can be reused to iinfect files on mobile devices. While the infection method that Duts uses is simplistic and requires user intervention, it is likely that advanced techniques will appear on mobile platforms and will more closely resmble the evolution of PC viruses. The current techniques are present, and the ability to propogate the code is evident. The current trends and outbreaks are few only as a result of the limited number of devices and the relatively new developers environmet. Nevertheless, MMS (Multimedia Messaging Service) worms, Classic viruses, and backdoor trojans, are all feasible on these devices. Beware, as more mobile computing devices become more sophisticated and complex, it is likely that more avenues of attack will become evident.

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25 Gigabytes of storage from one ear of corn!

Researchers at consumer electronics maker Pioneer have developed an optical disk made of corn starch resin that can hold 25 gigabytes of data,a dn is almost completely biodegradable. A single ear of corn can produce 10 discs. Also if the starch polymer is incinerated it will not eliminate any dioxins (think of vladimir yushenkov's poisoning), or other harmful chemicals. The disc are even edible, but with an extra durable 0.1 mm coating it is imposible to chew. (Baseline, 038, December 2004)

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French is trying to catch up to the us, and Germany.

Currently, more than half of Europe’s nanotechnology companies are from Germany and of all the patent applications from across the world, German researchers are only beaten by the Americans in terms of quantity.
In response, Research Minister Francois D'Aubert said the government will raise its investments in nanotechnology research and development to 70 mln eur per year from 2005-2007, up from 30 mln currently.

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Suprnova.org shut down, possibly by the MPAA

A note posted on Suprnova.org, which facilitated sharing among users of the BitTorrent program, said the site was "closing down for good." The collection of links to downloadable files, including music, movies and books, was taken down."We are very sorry for this, but there was no other way, we have tried everything," the statement said.Suprnova.org the most popular repository for links to files that could be downloaded using the BitTorrent program.
Another site that carried BitTorrent links, N4p.com, said it had shut down due to a civil complaint that cited the Digital Millennium Copyright Act. Torrentbits.org and Phoenix-torrents.com also shut down.Still, there were plenty of sites with BitTorrent links alive on Monday, including a "mirror," or copy, of Suprnova.org.BitTorrent has grown quickly in popularity this year, and now accounts for more than a third of all traffic on the Internet, according to the research company Cachelogic.The program owes its popularity in part to its immunity to industry attempts to confound it with bogus decoy files, which have swamped some other networks. BitTorrent also allows for efficient and speedy downloads.
MPAA will go after DirectConnect and eDonkey file-swapping services, inthe coming weeks.

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Israel and Uganda team up to create biosensors for viruses only calatogued in Uganda.

Israel and Uganda team up to create biosensors for thousands of unknows viruses that were only catalogued in Uganda before becoming outbreaks in the rest of the world. This includes Ebola,the west nile and others....

Dec. 5, 2004 8:42
Entebbe, Beersheba scientists cooperate to fight viruses
By JUDY SIEGEL-ITZKOVICH: Jerusalem Post

There are dozens of mysterious viruses in developing countries that could spread to the Western world or be used by terrorists. In light of this, Israeli researchers have joined counterparts in Uganda to try to understand the pathogens and the best way to fight them.

Scientists at Ben-Gurion University of the Negev were the first in the world to go to Uganda and study blood samples from victims of the ebola virus - which killed nearly 300 people four years ago. They plan to go back for a second visit soon.

Two Ugandan virologists are here for the first time attending a BGU conference on bioterrorism. They are Julius Lutwama and Elly Rwaguma of the Uganda Virus Research Institute in Entebbe.

The institute in Entebbe and BGU now have a formal cooperation agreement on the study of such viruses.

The two-day International Workshop on Defense to Biological Threats and Homeland Security, which ended on Thursday, was organized by BGU scientists Robert Marks and Leslie Lobel with help from the Ministry of Science and Technology, National Institute of Biotechnology director Prof. Irun Cohen and BGU health sciences faculty dean Prof. Rivka Carmi. Top scientists from Germany, Russia, Uganda, the US and Israel attended.

In an interview with The Jerusalem Post, Lutwama, a 45-year-old virologist and entomologist, said he was most interested in learning about biosensors to detect the presence of dangerous viruses early, before they kill large numbers of people.

Marks, from BGU's biotechnology engineering department, lectured on glowing fiber optic biosensors he pioneered that enable rapid detection of pathogens. Among them are biosensors for hepatitis C developed with Yonat Shemer-Avni, which detect antibodies in the blood of patients that could not be picked up by the standard assay. Marks is developing an ebola virus detection test with Lobel and a test for agro-terrorism with Menachem Banai of the Kimron Veterinary Institute at Beit Dagan. Lobel believes that the most effective way to control deadly infectious viral diseases such as ebola and smallpox is with human monoclonal neutralizing antibodies, since traditional antiviral treatments are rather ineffective and mass vaccination is dangerous and impractical in some cases.

In 2000, Lutwama and Rwaguma went to the Gulu region, the site of an outbreak of ebola that killed some 300 people and left fewer than 100 survivors. BGU funded an expedition to Gulu to draw blood specimens from 50 of them.

Lobel explained that because most virologists in the Western world have no access to enigmatic African viruses, they have not studied them. "In Uganda they've isolated hundreds of viruses that were unknown to the rest of the world, including the West Nile virus."

Lutwama said that "at the moment, ebola is not active, but two months ago, there was an outbreak in Sudan, where a number of people died."

Ebola is spread by contact with body fluids, and most of the victims were women who took care of sick people.

"Suddenly people started bleeding from their mouths and eyes and then anywhere on their skin. But people didn't reach the hospital early enough," Lutwama said. "There is no cure, but rehydration therapy and antibiotics, which deal with additional infections due to a weakened immune system, could have saved some of them."

His Entebbe lab is also maintaining surveillance of other viruses, such as onyong-nyong, which is usually not fatal but makes the victim feel like all his bones are broken, making it impossible for him to move. The virus is transmitted by same species of mosquitoes that spread malaria.


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Welcome to GIANTmicrobes!

With the holidays around the corner these are gifts you can't pass up. They will be talked about everytime a coworker comes to your desk.
"We make stuffed animals that look like tiny microbes'only a million times actual size! Now available: The Common Cold, The Flu, Sore Throat, Stomach Ache, Cough, Ear Ache, Bad Breath, Kissing Disease, Athlete's Foot, Ulcer, Martian Life, Beer & Bread, Black Death, Ebola, Flesh Eating, Sleeping Sickness, Dust Mite, Bed Bug, and Bookworm (and in our Professional line: H.I.V. and Hepatitis).
Each 5-to-7 inch doll is accompanied by an image of the real microbe it represents, as well as information about the microbe. "

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WHO plans for inevitable bird flu pandemic

WHO plans for inevitable bird flu pandemic: "The nerve center will be hooked up to 120 laboratories and surveillance centers around the world. "

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Virtual command center for the Worl Health Organization to fight Ebola, and other outbreaks.

The World Health Organisation today opened an emergency response centre to tackle illnesses that verge on becoming pandemic - such as bird flu and SARS - anywhere in the world in 48 hours.
"The need to be able to bring together scientists from all over the world, rapidly, in a virtual network, either through audio-visual or computer links, provides us with an ability to get the best minds in the world working on a public health problem immediately," he said.


The five million dollar room, which opened in August for testing, could quickly be redesigned and reshaped for different emergency uses. It has been equipped with dial-up, audio-visual conferencing in three areas, which can operate independently of power cuts, breakdown in telephone service, or other communication problems at WHO, he said.


"We don't need to get people together physically," Ryan said. "We can leave lab people working in their labs on the diagnostics. We can leave clinicians working on the frontlines in the hospitals, but we can bring them together virtually to exchange information rapidly during a crisis."

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Sunday, December 19, 2004

Biological implications of medicinal nanotechnology

Today’s Physicians are being constantly bombarded by the latest technology. But, where is all this stuff really coming from. The thrust is the quest to climb inside our bodies and repair the problem as easy as it is to simply stretch out our hands and straighten the pictures on out walls..... Take VivaGel as an example. VivaGel is being developed as a topical microbicide that has the potential to prevent the transmission of HIV and other STDs when applied to the vagina prior to sexual intercourse. In earlier studies performed in monkeys, VivaGel was found to be highly effective in preventing HIV transmission. VivaGel is the first drug product based upon nanoscale molecules called dendrimers to enter human trials under FDA Regulations. But this only involves the external microbes. Nevertheless, the University of Illinois in Champaign has created a tiny robot. This robot is not like the calculator that scientists in Israel created. It is designed to be implantable in humans, and give feedback. This tiny, implantable detector that could one day allow diabetics to monitor their glucose levels continuously—without ever having to draw a blood sample. the new sensors are based on single-walled carbon nanotubes: cylindrical molecules whose sides are formed from a lattice of carbon atoms. The idea is to exploit the nanotubes’ ability to fluoresce, or glow, when illuminated by certain wavelengths of infrared light—“a region of the spectrum where human tissue and biological fluids are particularly transparent,” They first coat the nanotubes with a “molecular sheath”: a one-molecule-thick layer of compounds that react strongly with a particular chemical—in this case, glucose. The mix of compounds is chosen so that the reaction also changes the nanotubes’ fluorescent response. They then illuminated the sample with an infrared laser and verified that the strength of the fluorescence from the buried sensor was directly related to the glucose concentrations in the tissue. But implanting small machines is simply inserting. It does not mean we have the ability to change anything. We are simply shoving around huge quantities of atoms. We must be able to pick one up at a time and place it in the precise location we want to. Scientists have performed a delicate surgical operation on a single living cell, using a needle that is just a few billionths of a meter wide. In order to manipulate cells, scientists currently use tiny injectors called micro-capillaries to introduce molecules such as proteins, peptides and genetic material into cells. But the shape of these micro-capillaries and a lack of accuracy in controlling them often results in fatal damage to the cell.
Measuring the forces as the nano-needle penetrated their interiors.
"To the best of our knowledge, the results demonstrated for the first time that solid material was inserted into a nucleus of such a small living cell with highly accurate positioning," the team writes in Nano-Letters."We can inject metabolic inhibitors into cells through a nano-needle allowing it to be accepted by the cell's metabolic pathways," said Dr Nakamura. "This cell surgery allows us to modify the cell's functions. "Dr Nakamura aims to use the technique on embryonic stem cells. It could be used to control the cells' differentiation - the process by which cells become, say, heart, kidney or liver cells - and how they proliferate - or divide. Another laboratory has gone even further. A team of German scientists has succeeded in creating what they call DNA ‘velcro’ to bind and then separate nanoparticles. University of Dortmund, Christof Niemeyer and his team used strands of artificial DNA University of Dortmund, Christof Niemeyer and his team used strands of artificial DNA. The advent of nanotubes coupled with optical materials has led us to be able to place markers within the cells we are attempting to study. The latest tests bode well on two counts. Not only did the nanotubes retain their optical signatures after entering the white blood cells, but the introduction of nanotubes caused no measurable change in cell properties like shape, rate of growth or the ability to adhere to surfaces. Although long term studies on toxicity and biodistributions must be completed before nanotubes can be used in medical tests, the new findings indicate nanotubes could soon be useful as imaging markers in laboratory in vitro studies, particularly in cases where the bleaching, toxicity and degradation of more traditional markers are problematic. When we combine the effects of nanotubes and markers we get a new nanotechnology-based technique could lead to a test for diagnosing the early signs of Alzheimer's disease. The Bio-Barcode-Assay can recognise ADDL, a protein that accumulates in the brains of sufferers. It is a million times more sensitive than conventional tests and could revolutionise disease detection. "We have done the first set of experiments that quantify the number of ADDLs in cerebrospinal fluid," Professor Mirkin said. ADDLs are protein bundles which attack nerve synapses in the brains of people with Alzheimer's. Professor Mirkin said it could also lead to a test to diagnose breast cancer by detecting the faint presence of a protein called PSA, normally associated with prostate cancer in men. It could also form the basis of a new test for HIV and other diseases in blood screening."The next exciting step would be to move to blood. If you detect it in blood, you have a huge win." To perform a Bio-Barcode-Assay, researchers select antibodies on the basis of the biomarker they need to detect in a solution. Some antibodies are fixed to magnetic particles while others are attached to spherical gold particles just 30 nanometres in diameter. Strands of DNA are fixed to the gold nanoparticle. When antibodies bind to a target biomarker, it becomes sandwiched between a magnetic particle on one side, and a gold particle and its strands of DNA on the other. Applying a magnetic field brings this entire "complex" out of solution. Researchers then release the DNA strands and use a DNA detection device to recognise their signature sequences. The dream of monitoring a patient's physical condition through blood testing has long been realized. According to Hood, the focus of medicine in the next few years will shift from treating disease -- often after it has already seriously compromised the patient's health-to preventing it before it even sets in.
Hood explains that systems biology essentially analyzes a living organism as if it were an electronic circuit. This approach requires a gigantic amount of information to be collected and processed, including the sequence of the organism's genome, and the mRNAs and proteins that it generates. The object is to understand how all of these molecular components of the system are interrelated, and then predict how the mRNAs or proteins, for example, are affected by disturbances such as genetic mutations, infectious agents, or chemical carcinogens. Therefore, systems biology should be useful for diseases resulting from genetics as well as from the environment.
"Patients' individual genome sequences, or at least sections of them, may be part of their medical files, and routine blood tests will involve thousands of measurements to test for various diseases and genetic predispositions to other conditions
"The yeast model taught us many lessons for human disease, For example, when yeast is perturbed either genetically or through exposure to some molecule, the mRNAs and proteins that are generated by the yeast provide a fingerprint of the perturbation. In addition, many of those proteins are secreted. The lesson is that a disease, such as a very early-stage cancer, also triggers specific biological responses in people. Many of those responses lead to secreted proteins, and so the blood provides a powerful window for measuring the fingerprint of the early-stage disease." with a sufficient number of measurements, "one can presumably identify distinct patterns for each of the distinct types of a particular cancer, the various stages in the progression of each disease type, the partition of the disease into categories defined by critical therapeutic targets, and the measurement of how drugs alter the disease patterns. The key is that the more questions you want answered, the more measurements you need to make. It is the systems biology approach that defines what needs to be measured to answer the questions."
you imagine the pathway toward predictive medicine rather than reactive medicine About 100,000 measurements on yeast were required to construct a predictive network hypothesis. The authors write that 100,000,000 measurements do not yet enable such a hypothesis to be formulated for a human disease. Need technologies, ranging from microfluidics to nanotechnologies to molecular-imaging methods.
Take for example nanosized quantum dots which light up when exposed to ultraviolet light making it possible to detect, target and kill cancer cells.
how a virus infects a cell. they tag them with some sort of transceiver and monitor the signal.
he started to examine quantum dots — nanoscale particles of semiconductors — as possible alternatives to the dyes.
they can last for over 48 hours The colour of light they emit can be changed by altering their size, with smaller dots emitting blue, green or yellow light and larger dots appearing orange, red or brown. “We can basically custom design the properties of the materials for whatever applications we need.”
Still, a major challenge remains. Quantum dots normally have a very oily surface the dots wouldn’t do well inside the water-based cellular environment. Chan is now looking for ways to modify the surface chemistry so that they interact with water-friendly molecules like proteins and DNA.
“When cells are diseased, they produce a unique set of proteins on their surface. If you find a matching molecule [to those proteins], you can take whatever you want to that site,” “Light can only penetrate so far into the body. You can screen for surface cancers but the deeper the cancer, the harder it is to screen using quantum dots as a technique.”
The quantum dots are made of potentially toxic heavy metals which, because of their size, can find their way into body structures that other materials can’t. “Nanotechnology has the potential to have many applications like contrast agents, biosensors and new diagnostic schemes,” how does your body deal with these materials
will also use the quantum dots to bring drug therapies to the disease site. Beyond cancer, could be used to detect pathogens such as malaria and HIV and he estimates that his quantum dots could be lighting up human disease within five to 10 years.

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Better cooling systems means we are much closer to everyday supercomputers.

Friday, NASA teamed up with Nanoconduction Inc. to help climb into the world of carbon nanotubes. They are both looking to improve the way electronics are staving off the heat. Although, NASA has other intentions besides cooling off electronics. They are looking to: 1.cool space stations with new materials, and 2.make the electrical components smaller and lighter, while the private sector is looking for ways to cool the chips, and make them smaller. They both, of course, are looking for faster and more efficient performance.
If you look at the report regarding quantum encryption (I am a bit slow in writing it, look for it in the next few days, sorry) you will see that both sectors are now finding that to control both quantum computers and quantum encryption you need to supercool the material (to at least impart distance, you can't 'boost' the photonic spins as this will change it's positioning). The states of the quantum spins are reliant on minimal 'noise' these new chips, as appose to the Gallium-Arsenide ones, will be able to efficiently control the thermal conductivities.
In other projections, their are various teams in Chicago that are taking a new approach to this same problem. By understanding the mechanism that cause conformational changes in proteins we can, hopefully, couple this to the new Buckey-ball shapes, and carbon nanotubes, and not only create and efficient thermal management system but also allow it to adapt to the rapidly changing environments.
For example if we apply it to the exterior of the MIR. The rotations and constant fluctuations in heat and cold (based on which side of the earth they are on) will be able to not only hold the heat inside, but will also be able to change shape and trap the heat inside Buckey-ball 'canisters", they are extremely efficient in the game of enthalpy, and then release it upon predestined temperature markers. Which will be, of course, nanostructures that have very specific values.
Think of organic element that release color at very precise values. We are finding new ways to understand and control these methods as well. (see the article on BRET Fluorescence). The small company called EnviroSystems based in San Jose uses nanotechnology to allow their cleaners to penetrate the cell walls of bacteria. They have engineered their chemical to clean, kill, and yet remain to be very eco friendly. This application is quite the reverse of what NASA is doing. The new cleaner was engineered backwards by having the chemical and then amplifying it, and although they won’t say, by making it be very cell specific. This allows it to not enter the human cell and explode it. They are calling projections in the eight figures for this year. (With a company of only 12, and $20 a gallon, damn!)
The carbon nanotubes NASA will be trying to engineer are already being used. We saw in mid 2004 that when organophosphates are coupled to nanotunes the nanotubes can be connected to a sensor that is coupled to a laptop. The organophosphates are distributed like a micro assay and can detect materials on the environment. More specifically when they were coupled to neurotransmitter enzymes (the things that initiates propagations and action potentials) the minute particles in nerve agents and chemical warfare can be detected instantly and the appropriate measures can be taken to combat it. The carbon nanotubes are so specific they can detect traces in as few as 5 parts per Billion.


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Spammers must pay $10B to ISP

ISP Awarded $1 Billion in Anti-Spam Suit

DAVENPORT, Iowa (AP) - A federal judge has awarded an Internet service provider more than $1 billion in what is believed to be the largest judgment ever against spammers...

Robert Kramer, whose company provides e-mail service for about 5,000 subscribers in eastern Iowa, filed suit against 300 spammers after his inbound mail servers received up to 10 million spam e-mails a day in 2000, according to court documents.

U.S. District Judge Charles R. Wolle filed default judgments Friday against three of the defendants under the Federal Racketeer Influenced and Corrupt Organizations Act and the Iowa Ongoing Criminal Conduct Act.

AMP Dollar Savings Inc. of Mesa, Ariz., was ordered to pay $720 million and Cash Link Systems Inc. of Miami, Fla., was ordered to pay $360 million. The third company, Florida-based TEI Marketing Group, was ordered to pay $140,000.


``It's definitely a victory for all of us that open up our e-mail and find lewd and malicious and fraudulent e-mail in our boxes every day,'' Kramer said after the ruling.


Kramer's attorney, Kelly Wallace, said he is unlikely to ever collect the judgment, which was made possible by an Iowa law that allows plaintiffs to claim damages of $10 per spam message. The judgments were then tripled under RICO.


``We hope to recover at least his costs,'' Wallace said.


There were no telephone listings for the three companies in Arizona and Florida. Nobody replied to an e-mail sent Saturday to Cash Link Systems.


According to court documents, no attorneys for the defendants were present during a bench trial in November. The lawsuit continues against other named defendants.


Laura Atkins, president of SpamCon Foundation, an anti-spamming organization based in Palo Alto, Calif., said she believed it was the largest judgment ever in an anti-spam lawsuit.


``This is just incredible,'' she said. ``I'm not aware of anything that's been over $100 million.''



12/18/04 15:26


© Copyright The Associated Press. All rights reserved. The information contained In this news report may not be published, broadcast or otherwise distributed without the prior written authority of The Associated Press.

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A clustering search engine (Google still doesn't have this!)

I must admit I am a steadfast Google user, fan, promoter. Yet I bumped across this site and although I don't think I will use it regularly I thought it had a neat feature that even Google should implement, barring any copyright infringments. The clustering of resluts into folders based on returned content is pretty helpful. In the case of "Ubiquitin" it returned various segemented options. for example it catagorized it as "Medical", "Antibodies", "Cycle and Ubiquitine", "Human", "Proteasome", "Cell Biology", and a multitude of others. Give it a whirl for yourself. I may crawl back to it when I am totally clueless about what i am searching for and it does not pop up under Googles define or perhaps Googles Suggest has nothing for me. I think that it can serve as a oerfect tool for the student. For example, if they needed to write a paper on the "Marburg Virus" all I had to do was type in the name and I would immediately get various catagories to choose each of my papers paragraphs to cover. It is seamless because for each idea you have a perfect set of papers, websites, and resources to choose from in that catagory. I also tested it on "Gun Cntrol" it gave me ten perfect catagories. I also can click on each one and get a whole new internal set to write evidence for within the paragraphs main idea.
well enough, go try it out yourself. let me know what you think.

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Wired News: A Patch for Broken Hearts

Niklason, who was the first to grow functional human arteries in 2003 has now successfully grown heart cells that she got to beat regularly and in sync.
The researchers started by attaching rat cardiac cells to a three-dimensional collagen scaffold, which acts as a frame for the cells to grow on and then dissolves. They zapped the cells with electrical pulses modeled on a rat heartbeat for several days, inducing them to grow into beating patches about the size of a dime, according to research published this week in the Proceedings of the National Academy of Sciences online...Continue.


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Alcohol fuel cells goes micro!

Alcohol Fuel Cell Goes Micro
The battery life of electronic devices, particularly mobile devices, has been the bane of existence for travelers. While there have been giant leaps in processing speed and power for handhelds and laptops, there have been only tiny steps with power sources.

While fuel cells may eventually be the key to longer life, there is much hope that research on magnetic RAM will extend battery life. Here is a look at IBM-Infineon's much-balleyhooed MRAM project. -- Brad King

There's a lot of energy in ethanol, which is non-toxic and can be made cheaply from corn.

Researchers from Saint Louis University, who earlier this year developed a fuel cell using enzymes to generate electricity from ethanol, have built a microchip-based version of the device.

The trick to constructing the biofuel cell was creating a sheltered environment for the enzymes, which are fairly sensitive. The researchers coated the carbon anode, or positive electrode, of the fuel cell with polymethylene green, an electocatalyst, then added a nafion membrane containing the immobilized enzyme alcohol dehydrogenase.

The biofuel cell showed an electrical potential of 0.34 volts and current density of 53 microamps per square centimeter, according to the researchers. Multiple cells can be stacked, and the device can be integrated into a computer chip.

The microchip biofuel cell could eventually be used in place of rechargeable batteries. Instead of recharging by plugging into a wall outlet like batteries, the biofuel would be recharged by adding a few milliliters, or thousandths of a liter, of alcohol. The micro fuel cell could also be used to power sensors and labs-on-a-chip.

The researchers' prototype consists of a 200-micron-wide, three-centimeter-long channel in a plastic chip. The bottom of the channel is lined with the carbon anode, which is covered by the electric catalyst and membrane. The researchers tested the fuel cell by measuring the electricity generated as one microliter, or millionths of a liter, per minute of ethanol flowed through the channel. A drop of water contains about 50 microliters.

The biofuel cell's enzyme catalysts are renewable. Most fuel cells catalyze reactions with metals, which are relatively expensive and not renewable.

The work is scheduled to appear in an upcoming issue of Lab-on-a-Chip.

Technology Research News


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France puts seven spy satellite into orbit.

PARIS - A European rocket roared into space from a pad in South America on Saturday, placing into orbit a surveillance satellite billed as giving France's military new abilities to spy worldwide.The unmanned craft lifted off smoothly from a launch center in Kourou, French Guyana, the third and last launch of an Ariane-5 rocket this year, Arianespace said.The satellite and six smaller scientific ones were placed into orbit about an hour after liftoff. It was the first time in 11 years that an Ariane rocket carried as many as seven satellites on a single launch.
Click read more to find out what each one does, or what France claims they will do.
The Helios 2A military satellite, the rocket's main cargo, is to rotate in sun-synchronous orbit about 435 miles above the Earth, Arianespace said."The success of the Helios 2A launch is a great step forward for our space policy," Defense Minister Michele Alliot-Marie said at Ecole Militaire. "Mastering space is an imperative for tomorrow," she said, calling for greater space cooperation in Europe.The French military will "benefit from additional capabilities, more precise images and faster reaction speed," she said at the Paris academy.Among expected functions, the satellite is to monitor possible weapons proliferation, prepare and evaluate military operations and digitally map terrain for cruise missile guidance, the French Defense Ministry said in a statement Friday.Helios 2A, weighing 4.6 tons, is said to be able to spot objects as small as a textbook anywhere on Earth. Equipped with infrared sensors, it is expected to allow France's military to gather information at night from space for the first time.Among its predecessors, Helios 1B, which was launched in 1999, suffered a power problem, and the military let it disintegrate in the upper layers of the atmosphere two months ago. The first satellite in the series, Helios 1A, went up in 1995 and is still operating.Also in the payload Saturday was the Parasol satellite, which is to help study the effect of cloud cover and aerosols on global warming and the greenhouse effect, believed to occur when carbon dioxide emissions trap the sun's heat in the atmosphere.
This was reported by Jean-Marie Godard of the Associated PressDec. 19, 2004 12:00 AM


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Wired News: Smaller Is Better on Battlefield

Medical equipment is becoming smaller, and more powerful. Our surgical centers are being brought to the patient out in the battlefields. Blood-testing is being crammed into tiny devices with multiple tests done to each drop of blood, ultrasound, oxygen concentrators, and ventilators are being compressed.

The equipment is "reduced in size and weight enough that a handful of people can carry it all inside a few Humvees, set it all up within an hour and have all the equipment for (the) first two operations inside of five backpacks," said surgeon Dr. Atul Gawande, a Harvard School of Public Health assistant professor and journalist who wrote about the state of military medicine in the Dec. 9 issue of the New England Journal of Medicine.

Read the full article
Wired News: Smaller Is Better on Battlefield


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Polymer Science enables new breakthroughs in IT and medicine

Polymer Science enables new breakthroughs in IT &Nano Medicine

How about storing terabytes of information on a digital video disc (DVDs) or wearing a plastic health card that stores x-rays, ECG, blood test reports, MRI scans and other information on a bracelet. These technologies have been made possible by advancements in polymer science according to Paras N Prasad, Distinguished Professor at University of Buffalo, New York....
Delivering a plenary lecture at Macro, 2004, the international conference on polymers for advanced technologies organized by Society for Polymer Science, India, Prof Prasad said that conventional DVD,s contain only two layers while the deployment of polymeric material can create hundreds of layers which can store terabytes of information on the same disc. Plastic health cards embedded on bracelets will enable the medical team to immediately attend to a patient in case of emergencies such as accidents or heart stroke as the entire medical history of the patient is recorded in this tiny device, Prof Prasad said.
The medical branch of nanotechnology, Nano-medicine has come up with new diagnostic techniques to detect diseases at an early age through real time monitoring that was not possible before. A new product called 'Nano-clinic' has been patented in the US and is used in the treatment of cancer. It is a small bubble that contains imaging components, therapeutic agents and diagnostic tools that help in the treatment of cancer when it is inserted into the body. The same technology is also used in gene therapy where a particular organ with deficient genes has to be injected with DNA carrying nano-particles for release inside the body.
In ophthalmology, a nano-glue has been devised which when embedded in the eye would release the medicine at fixed intervals thus making the life easy for the patient. Clinical applications of nano-medicine will take a longer time before it will be made available commercially.
The biotechnology wing of Sree Chitra Thirunal Institute of Medical Sciences have developed a technique to prevent formation of calcium deposits in polyurethanes used for making artificial heart and heart valves. The technique involves creating polypeptide or amide linkages in the devices that will resist the formation of calcium deposits. The calcification of polyurethane heart valve leads to stiffening and failure of flexural performance of the valve.
Thiruvananthapuram, Dec 17


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The military developed one better than the latest jackets on the market (see yesterdays post)

Working the military, emergency workers and doctors in this sunrise area, Bethesda, Md. based Sensatex, developed what it calls a 'smart shirt' - clothing having tiny microscopic wires interwoven into the fabric itself. Vital parameters like heart rate, respiration rate, body temperature, caloric burn, body fat, and UV exposure can be communicated to the doctors from the field itself....


Smart textiles offer wearable solutions using Nanotechnology 16th December 2004

Did you hear of a shirt that reads your body parameters and sends information to a remote computer through a wireless communication system?
Have you watched leading athletes perform better on the tracks due to smart fabrics they wear?
This is the wonder of Nano technology! The new age technology that optimises performance and provides smart solutions for the future.
Nano Technology means configuring molecules to change in size and properties for enhancement as in the case of smart fabrics.
When a glass trips on your trousers, its nanotech fabric will simply repel the juice drops. The Nano-Tex fabric coated with nanotech engineered molecules attach themselves to one another, and then attach to the fabric forming a nano shield against juice stains.
Nano-Tex, located at Emeryville, California, is another pioneer in the field has been acknowledged for rescuing Burlington Industries by turning its textiles into high-tech wonders.
Though Nano-Tex is available in chain stores and supermarkets, it may be coming to a soldier or police officer shortly.
World's 20 largest textile mills have acquired Nano-Tex licensing technology so far. You may soon get to wear its products as this revolutionary innovation begins to appear in every-day life, though invisible to the naked eye, as yet.
Working the military, emergency workers and doctors in this sunrise area, Bethesda, Md. based Sensatex, developed what it calls a 'smart shirt' - clothing having tiny microscopic wires interwoven into the fabric itself. Vital parameters like heart rate, respiration rate, body temperature, caloric burn, body fat, and UV exposure can be communicated to the doctors from the field itself.
Sensatex technology can be incorporated into any fabric (cotton, lycra, wool, silk, etc.) or blend of fabrics without effecting the look, feel or integrity of the fabric that it is replacing.The SmartShirt System integrates advances in textile engineering, wearable computing, and wireless data transfer to permit the collection, transmission, and analysis of personal health and lifestyle data.
“We haven't even begun the nano-revolution,” quips Sensatex CEO Robert Kalik. "Throughout society, the ability to unplug from wires and utilize smart textiles to gather the information and then disperse that information, that data, through wireless communications, will be really the textile of the future," Kalik adds.
“We're solving seemingly mundane but actually quite large problems like spill resistance, wrinkles, perspiration, odor in every day clothing,” said Nano-Tex CEO Donn Tice.



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The future of IT is nanotechnology

Just imagine hard drive capable of holding 1000 times as much data than those used in computers today. No, this is not something straight out of any science fiction. It is the future of electronics and computing supported by nanotechnology. The advances in nanosciences may one day shrink modern day desktop PCs to the size of wrist watches. It's not just the size that is going to matter, the nano-revolution is going to give a big boost to power sources, chip technology and semi-conductors...
What is nanotechnology? Nanoscience is the science that deals with substances in which one dimension is less than 100 nanometre (nm). A nanometre is one billionth of a metre and the diameter of human hair is about 50,000 nm. Nanotechnology is the technology of designing, fabricating and applying nanosystems. A nanosysytem is a system that is synthesised to a nanometre scale (a nanometre is a billionth of a metre and spans approximately 10 atomic metres). A nanocomputer is a computer whose fundamental components measure only a few nanometres, usually less than 100 nm. This need to be compared with the size of the smallest integrated circuit that is used in today's computers, this comes to around 350 nm.
What's the kind of advances going on in the field of nanoelectronics? There has been a plethora of revolutionary inventions in the last century that virtually changed the face of the world. This includes trains, planes, automobiles, telegraph and Internet. All these applications saw real money, in huge volumes, being made by those who were adventurous to explore the new possibilities. Nanotechnology may be said to be at a point that the Internet was in the pre-boom period. ie, the early 90's. Nanoelectronics means working at smaller and smaller levels which means more power, more speed, and more applications in almost all the electronic applications. Almost all the pioneers of infotech business are into serious work on nanoelectronics. In semiconductors, Intel and Advanced Micro Devices are working on 65 nm chips and beyond. Intel promises commercially available products by 2005 and AMD by 2006. Hewlett-Packard, Toshiba, Samsung, and Texas Instruments are all working on chip designs for sub-100 nm chips. IBM, with reportedly 700 nanotech-related patents, is working on millipede data storage, as well as, ultimately, the molecular computer. Motorola and Silicon Storage Technology are developing what they call superflash memory chips working at the 65 nm level. This, one day could be supplementing the advent of Magnetic RAM (MRAM). IBM is also trying to bring this breakthrough to market. MRAM promises the much-awaited ability to switch on your computer as you do your TV and receive immediate pictures. The next generation of light-emitting diodes (LEDs) is already entering the marketplace with organic light-emitting diodes (OLEDs) being featured in digital cameras being sold by Eastman Kodak. The biggest and most novel application of OLED technology is going to be the 'anywhere, anytime television. The company Cambridge Display Technology promises to deliver these screens, which made its fictional, screen debut in Spielberg film Minority Report .
What are the areas other than nanoelectronics that are finding exciting application of nanotechnology? Nanomaterials: Nanomaterials includes carbon nanotubes, fullerenes, nano-oxides, nanocrystals and nanopowders. The market for carbon nanotubes and fullerenes has an annual growth forecast of 173%. Nanomaterials is projected to grow at 30.6% per annum. Carbon Nanotechnologies, DuPont, Dow Chemical, Nanosys are some of the companies involved in serious research and development of nanomaterials. Japanese industrial giants, Mitsui, Mitsubishi and Hyperion Catalysis are all perfecting production processes to produce hundreds of tons of nanomaterials per annum. Nanobiotechnology: Novavax has been working for nine years on its proprietary micellar nanoparticle drug-delivery platform, a topical emulsion of oil, water, and lipids capable of being absorbed through the skin. Drugs developed on this platform is used for treatment of hot flashes in menopausal women. American Pharmaceutical Partners has received fast-track status for its novel nanoparticle-based drug, Abraxane, on the back of favorable phase 3 results for use in treating metastatic breast cancer. Skyepharma estimates treatment for 40% of drug candidates is abandoned at an early stage due to the body's inability to absorb the drug. The company's nanoparticulate drug-delivery technology promises to remove a lot of these barriers. Flamel Technologies, a Motley Fool Hidden Gems pick, has a nanoparticle delivery technology that improves the delivery of drugs without side effects. In another area of drug discovery, Advanced Magnetics is working on receiving final FDA approval for Combidex, an MRI agent that will aid in diagnosing cancerous lymph nodes vs. nodes that are simply inflamed or enlarged.
What is going to be the commercial future of nanoelectronics? The global nanosensor market will grow to $17.2 billion by 2012, according to research firm NanoMarkets, but it must overcome technical barriers to connect to other sensor networks. Market for biomedical nanosensors to reach approximately $800 million in 2008 and $1.2 billion in 2012. Nanosensors will be used to detect the presence of biotoxins, such as anthrax and smallpox, as well as radioactive materials. He projects such uses to make a market of $827 million in 2008 and $3.9 billion in 2012. Semiconductors provide the enabling technology for virtually all computation and communications systems. The Nanoelectronics Research Initiative over the next 15 years will create devices with features less than 10 nanometers -- or billionths of a meter -- in size, roughly 10 times smaller than in current state-of-the-art chips. NanoMarkets expects that the aerospace segment of the nanosensors market will reach $214 million in 2008 and $2.1 billion in 2012 and that the automotive segment will grow from $133 million to $1.5 billion over the same period.
PRADEEP KURUP


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S.Africa's ANC Accuses U.S. of AIDS Drug Cover-Up

By Rebecca Harrison
JOHANNESBURG (Reuters) - South Africa's ruling party has accused top U.S. officials of treating Africans like guinea pigs amid questions over testing of a key HIV/AIDS drug before a U.S.-backed roll-out of the treatment across the continent.
The African National Congress (ANC) said on its Web site U.S. health officials had "conspired" with German drug firm Boehringer Ingelheim to hide adverse effects of nevirapine when used to try to prevent mother-to-child HIV transmission.
Media reports have suggested tests on the drug's use with pregnant women in Uganda were flawed and that single-dose treatments of nevirapine could result in future drug resistance.
The United States has denied the charges and said while there were some procedural problems with the tests the results pointing to a dramatic reduction of HIV transmission were sound.
But the ANC issued a strong response late on Friday saying President Bush and his government, which distributed the drug across Africa in a high-profile gesture of support for the AIDS-ravaged continent, must be "held accountable" for inaction.
"(U.S. officials) entered into a conspiracy with a pharmaceutical company to tell lies to promote the sales of nevirapine in Africa, with absolutely no consideration of the health impact of those lies on the lives of millions of Africans," the ANC said in its weekly newsletter.
Quoting reports by the news agency Associated Press, which first ran the story, the ANC said top officials at the U.S. National Institutes of Health (NIH) and the U.S. Food and Drug Administration (FDA) had arranged to pull a U.S. application for the drug once concerns were raised.
"NO BEARING ON SAFETY"
The ANC quoted the report as saying the NIH knew about problems with the drug but did not tell the White House before Bush launched a plan to distribute the drug throughout Africa.
There was no immediate response from the U.S. government to the ANC charges.
But the U.S. National Institute for Allergy and Infectious Diseases (NIAID), a unit of the U.S. National Institutes of Health and which funded the study, denied in a statement on its Web site dated Dec. 17 that NIH officials chose not to inform the White House about safety issues concerning the drug. NIAID said only procedural problems had been identified at the point the president was to announce his AIDS program.
"NIH officials did not directly inform the White House of these procedural problems identified in early 2002 because they had no bearing on the safety and efficacy of single-dose nevirapine used to prevent mother-to-infant transmission of HIV," NIAID said.
Privately-owned Boehringer Ingelheim said on Saturday nevirapine was not ideal but served a purpose in Africa and that no adverse effects had been recorded apart from when it was used as a long-term therapy, rather than a short-term treatment for pregnant women.
"Nevirapine is not the optimal solution, but it is working and there is no better help in very poor countries to prevent HIV-positive mothers passing the virus on to their children," a company spokesman said in Germany.
The company said on its Web site a 2002 audit of Ugandan site where the study occurred was sent to the NIH, Ugandan and U.S investigators "to encourage prompt correction of observed procedural deficiencies prior to the planned FDA audit."
FEAR OVER WRANGLING
It said the FDA audit was canceled because the Ugandan study could not correct the problems in time to satisfy a regulatory time frame, but that the overall conclusions regarding the safety of the drug "have remained intact."
The NIAID said it had asked the Institute of Medicine, a part of the U.S. National Academy of Sciences, to conduct an independent review of the study.
HIV/AIDS killed up to 2.2 million Africans last year and around two thirds of the 38 million people worldwide with AIDS live in sub-Saharan Africa, according to the United Nations. South Africa has the highest AIDS caseload in the world.
Doctors and AIDS activists in Africa have expressed concern that wrangling over nevirapine may prompt governments to halt the use of the antiretroviral drug, which is credited with protecting thousands of babies from infection.
South Africa President Thabo Mbeki's spokesman declined to comment on whether the ANC newsletter reflected the views of the president, who has been criticized for being too slow to respond to HIV/AIDS, which affects one in nine South Africans. (Additional reporting by Frank Siebelt in Frankfurt)
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